Session 9-4

A CMOS Sigma-Delta Photodetector Array
for Bioluminescence-Based DNA Sequencing

 

Abstract

A fully-integrated photodetector array for long-read length bioluminescence-based DNA sequence-by-synthesis is implemented. Each pixel has 120dB photocurrent detection dynamic range and includes a 10fA-10nA pulse frequency modulation (PFM) background subtraction block and a 1st-order Σ-Δ modulator.